# Sliding Filament Theory acetocolene and neurotransmitters and muscle movement (causes muscle contraction here) ## actin and myosin - the thick and thin filaments the filaments that do the work excitation contraciton coupling myosin connects and pulls **myosin pulls** myosin head is where the it binds it keeps going as long it has requirements met ### Step 1 excitation it has depolorization of the membrane ### Step 2 excitation propocation into a t-tubule - leads from the muscle fiber(cell) to inside sarcoplasmic reticulum (sr) sarco is calcium storage for muscles ### Step 3 excitation releases calcium once the sarco is excited/depolarized ### Step 4 excotation calcium moves toropomiasin to expose the active sites for contraction to occur Cross bridge cycle aka contraction (4 steps) ### step 5 myosin head connects to the newly exposed active site (actin and myosin automatically bind) ### step 6 stored energy used to pivot to pull pulls actin strand/shortens muscle (aside)(muscle cramps) muscles stuck in position without energy to release the myosin ### step 7 releses myosin from the active site ### step 8 atp broken down to reset relaxation ### step 9 neural signal ends